Case Studies

Benefits of Participation in high-risk activities in the outdoors (The Business Perspective)

In the outdoors we have implied knowledge, in that we believe swimming in the outdoors for example is better for you than swimming in a pool. Working with the School of Sport, Health and Excercise Sciences at Bangor University allows Surflines to research and test those theories. We’ll be able to translate the research and inform potential about the advantages of outdoor activities.

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Artificial defence structures as surrogate habitats for natural rocky shores: giving nature a helping hand (Presentation)

The UK’s Marine Policy Statement advises that in addition to avoiding harm to the environment, marine developments should also include “beneficial features” for marine wildlife. However, much remains unknown about the potential for manmade structures to deliver ecological benefits and surrogate for natural rocky shore habitat. Our research investigates the role of coastal defences in providing substrate for marine plants and animals to colonise. It also explores the potential to manipulate structures in order to achieve more beneficial outcomes from coastal defence developments.

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A Controlled Evaluation of a Food Dudes Healthy Eating Programme for children in Special Schools

Wales is an obesity hotspot, with the 5th highest child obesity rates of 35 OECD countries: in 2010, 36% of Welsh 2-15 year olds were overweight and 19% of these were obese. The literature shows that these rates are typically doubled for children attending Special Schools. These children often show change resistant behaviours such as idiosyncratic eating patterns and reluctance to try new foods, presenting the researchers with additional challenges. Although it is known that they are more likely to develop health problems and obesity than their peers in mainstream schools, they have been entirely overlooked in the existing research until now.

My Masters Research project has involved implementing the Food Dudes programme in special schools. The Food Dudes progarmme is based on the three psychological principles: role-modeling, rewards and repeated tasting. The intervention is split into two phases: the Intensive Phase (16 days) and the Maintenance Phase (rest of the academic year).

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Testing of a Mattress Design on Sleep Quality of those with Low Back Problems (Presentation)

The paucity of research in to sleep surfaces, sleep quality and back problems is surprising as we spend approximately a third of our lives asleep and 84% of the UK population will be afflicted with low back pain at some point in their lives.

The project will provide an objective assessment of mattress design in relation to back pain. A three month, double blind randomised controlled crossover study will take place in the participants own homes to ensure the most natural sleep environment.

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Development of a novel quinone prodrug delivery system for cancer (Presentation)

The chemotherapy agents which are in current use are highly toxic compounds and are also non selective meaning that in effect the patient is being medically “poisoned” in the hope that the cancer will die first. Prodrug technology allows for the selective deployment of highly toxic drugs into cancer cells, whilst healthy cells are left relatively unaffected.

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Development of products for controlled releasing topical and transdermal drugs using nano/micro-encapsulation and microneedles (Presentation)

This research project aimed to design a controlled release drug delivery using PLGA and PCL microspheres in conjugation with hydrogel patches. It is believed that development of such a novel drug delivery system would be use for treatments of many dermatological conditions such as Psoriasis and Eczema.

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The development of sensitive methods to quantify specfic antibodies directed against Clostridium difficile toxins and their use to provide improved immunotherapeutic products (Presentation)

Over the past decade the ‘superbug’, Clostridium difficile, has become the most common hospital acquired infection in the developed world. Epidemic strains have emerged which exhibit enhanced virulence factors including multidrug resistance, increased capacity to form highly resistant spores and produce significantly more toxins A and B than conventional strains. This project with MicroPharm, a small bio-pharmaceutical company based in West Wales, looks at recombinant fragments based on C. difficile toxins A and B that have been used to raise antibodies in sheep.

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Effect of rumen lipases on ruminal lipid metabolism (Presentation)

Student: Cate Williams Company: Hybu Cig Cymru Academic Supervisor: Dr Sharon Huws The effect of rumen bacterial lipases on ruminal lipid metabolism The relationship between SFAs and chronic diseases, such as coronary heart disease, are well established, and despite providing many essential vitamins and minerals, red meat suffers much negative stigma. This confusion has developed… Read more »

Development of a Food Dudes Healthy Eating and Activity Programme for preschool children in nursery settings, and their families at home (Presentation)

My project is in collaboration with Food Dudes Health Ltd, who already have an award winning Healthy Eating Intervention and are now keen to develop a physical activity intervention to tackle the ongoing issue of obesity.

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Screening of a plant derived natural produt library for anthelmintic properties (Presentation)

The MPhil project was supported financially by the KESS scholarship which allowed the collaboration of a Welsh SME, PhytoQuest, and the Hoffmann Parasitology research group at Aberystwyth University. This collaboration has allowed for a screen of extremely pure plant-derived compounds, provided by the Welsh industrial collaborator, to be performed assessing the selective activity of the library against a species of parasitic worms of veterinary and biomedical importance.

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