Case Studies: Health Sciences

Enhancing technology to improve patient care

Huntleigh Healthcare

Peripheral Arterial Disease (PAD) is the less well-known branch of cardiovascular disease which relates to the narrowing or obstruction of the arteries in the legs. Previous research has shown that individuals with PAD have a three-to-six-fold increased risk of cardiovascular death compared to those who don’t have it. The main symptom of PAD is pain in the legs when… Read more »

The development of sensitive methods to quantify specfic antibodies directed against Clostridium difficile toxins and their use to provide improved immunotherapeutic products (Presentation)

Over the past decade the ‘superbug’, Clostridium difficile, has become the most common hospital acquired infection in the developed world. Epidemic strains have emerged which exhibit enhanced virulence factors including multidrug resistance, increased capacity to form highly resistant spores and produce significantly more toxins A and B than conventional strains. This project with MicroPharm, a small bio-pharmaceutical company based in West Wales, looks at recombinant fragments based on C. difficile toxins A and B that have been used to raise antibodies in sheep.

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